Description
ATXN3 Polyclonal Antibody | E-AB-40246 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Lead Time: 7~10 days
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Ataxin-3 protien
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 41 kDa
Observed Molecular Weight: 41 kDa, 22 kDa
Clonality: Polyclonal
