ATXN3 Polyclonal Antibody | E-AB-40246

ATXN3 Polyclonal Antibody | E-AB-40246 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Ataxin-3 protien

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 41 kDa

Observed Molecular Weight: 41 kDa, 22 kDa

Clonality: Polyclonal