Description
ATG5 Monoclonal Antibody | E-AB-22149 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Application: WB, IHC-p
Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Background: Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Protein of ATG5
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Protein A purification
Dilution: WB 1:500-2000, IHC 1:50-300
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: 55 kDa
Clonality: Monoclonal
