ATG5 Antibody | V8239-100UG

ATG5 Antibody | V8239-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: AGT5/3220R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: ELISA

Application Details: ELISA: order Ab without BSA for coating

Application Note: Optimal dilution of the recombinant ATG5 antibody should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

Immunogen: A portion of amino acids 1-119 from the human protein was used as the immunogen for the recombinant ATG5 antibody.

Storage: Store the recombinant ATG5 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cytoplasmic