Description
ATG5 Antibody | V3951-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: ATG5/2101
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, WB, IHC-P
Buffer: N/A
Limitation: This ATG5 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.
Immunogen: A portion of of amino acids 1-119 from the human protein was used as the immunogen for the ATG5 antibody.
Storage: Store the ATG5 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).