Description
ATG5 Antibody | F46219-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, IF, ELISA
Buffer: N/A
Limitation: This anti-ATG5 antibody is available for research use only.
Purity: Antigen affinity
Description: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Immunogen: A portion of amino acids 209-238 from the human protein was used as the immunogen for this anti-ATG5 antibody.
Storage: Aliquot the anti-ATG5 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
