ATG4B Antibody | N1210-100UG

ATG4B Antibody | N1210-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB

Buffer: 1X PBS, pH 7.4

Limitation: This ATG4B antibody is available for research use only.

Purity: Protein A affinity chromatography

Description: Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ‘autophagy-related gene’ ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.

Immunogen: A recombinant protein fragment from the C-terminal region of ATG4B was used as the immunogen for this antibody.

Storage: Aliquot the ATG4B antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.