Description
ATF6 beta Antibody | F49022-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Hamster, Mouse
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This ATF6 beta antibody is available for research use only.
Purity: Antigen affinity
Description: ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
Immunogen: A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.
Storage: Aliquot the ATF6 beta antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
