ATF6 beta Antibody | F49022-0.08ML

ATF6 beta Antibody | F49022-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Hamster, Mouse

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This ATF6 beta antibody is available for research use only.

Purity: Antigen affinity

Description: ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

Immunogen: A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.

Storage: Aliquot the ATF6 beta antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.