ATF4 Polyclonal Antibody | E-AB-60006

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SKU:
575-E-AB-60006
Weight:
1.00 KGS
€1,012.00
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Description

ATF4 Polyclonal Antibody | E-AB-60006 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: WB, IF

Research Area: Cancer, Epigenetics and Nuclear Signaling

Background: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human ATF4 (NP_001666.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 38 kDa

Observed Molecular Weight: 50 kDa

Clonality: N/A

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Additional Information

Size:
120 μL
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