ATF3 Antibody | F44888-0.4ML

ATF3 Antibody | F44888-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This ATF3 antibody is available for research use only.

Purity: Antigen affinity

Description: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Immunogen: A portion of amino acids 140-168 from the human protein was used as the immunogen for this ATF3 antibody.

Storage: Aliquot the ATF3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.