Description
ASCL1 Antibody (Achaete-scute homolog 1) | F47525-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This ASCL1 antibody is available for research use only.
Purity: Antigen affinity
Description: This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Immunogen: A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
Storage: Aliquot the ASCL1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
