ARL2BP Polyclonal Antibody | E-AB-52822

ARL2BP Polyclonal Antibody | E-AB-52822 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: IHC, ELISA

Research Area: Cancer, Signal Transduction

Background: ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.ARL2BP (ADP Ribosylation Factor Like GTPase 2 Binding Protein) is a Protein Coding gene. Diseases associated with ARL2BP include Retinitis Pigmentosa With Or Without Situs Inversus and Arl2bp-Related Retinitis Pigmentosa. Among its related pathways are Integration of energy metabolism and Metabolism. GO annotations related to this gene include transcription coactivator activity and GTPase regulator activity.

Lead Time: 7~10 days

Concentration: 0.84 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ARL2BP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: IHC 1:20-1:100, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: Polyclonal