ARF6 Polyclonal Antibody | E-AB-40035

ARF6 Polyclonal Antibody | E-AB-40035 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Signaling transduction

Background: ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton.This antibody can bind ARFs for the close sequences.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human ADP-ribosylation factor 6 protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 20 kDa

Observed Molecular Weight: N/A

Clonality: Polyclonal