Description
Aquaporin 0 Antibody | R31222 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This Aquaporin 0 antibody is available for research use only.
Purity: Antigen affinity
Description: Aquaporin 0, also called Lens fiber major intrinsic protein, MIP26 and MP26, is a protein that in humans is encoded by the MIP gene. It is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. Using 2-color fluorescence in situ hybridization on high-resolution R-banded chromosomes and human genomic DNA clones for MIP as probes, this gene was found that located in close proximity in region 12q13. MIP/Aquaporin 0 plays a crucial role in the development of a transparent eye lens. This gene may be responsible for regulating the osmolarity of the lens and interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.
Immunogen: An amino acid sequence from the C-terminus of mouse Aquaporin 0 (NGQPEGTGEPVELKTQAL) was used as the immunogen for this Aquaporin 0 antibody (100% rat homology).
Storage: After reconstitution, the Aquaporin 0 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.