ApoE Antibody (Apolipoprotein E) | F50536-0.4ML

ApoE Antibody (Apolipoprotein E) | F50536-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This ApoE antibody is available for research use only.

Purity: Antigen affinity

Description: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Immunogen: A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody.

Storage: Aliquot the ApoE antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.