Description
APC11 Antibody / ANAPC11 | F53960-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This APC11 antibody is available for research use only.
Purity: Antigen affinity
Description: Anaphase-promoting complex subunit 11, together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Immunogen: A portion of amino acids 56-94 from the human protein was used as the immunogen for the APC11 antibody.
Storage: Aliquot the APC11 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
