Description
APC-Labeled Human Mucin-1 / MUC-1 Protein, His Tag (Site-specific conjugation) | MU1-HA2H8-25tests| Gentaur Distribution US, UK & Europe
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
Source: APC-Labeled Human Mucin-1 Protein, His Tag (MU1-HA2H8) is produced via conjugation of APC to Human Mucin-1 Protein, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human Mucin-1 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 890 - Gly 1158 (Accession # P15941-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Ser 890 - Gly 1158.
Conjugate: APC Labeled.
Molecular Weight: 21.3 kDa (partial α chain) & 10.2 kDa (partial β chain).
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.3 kDa (partial α chain) & 10.2 kDa (partial β chain).
Purity: N/A.
Buffer: PBS, 0.5% BSA, pH7.4.
Storage Conditions: -20℃, aviod light.
Shipping Conditions: RT