Description
APC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag (Site-specific conjugation) | CLA-HA248-200tests| Gentaur Distribution US, UK & Europe
CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Source: APC-Labeled Human CLEC12A, His Tag (CLA-HA248) is produced via conjugation of APC to Human CLEC12A, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human CLEC12A, His Tag is expressed from human 293 cells (HEK293). It contains AA His 65 - Ala 265 (Accession # NP_612210.4).
Format: Powder.
Tag: N-10×His.
Expression System: HEK293.
Expression Region: His 65 - Ala 265.
Conjugate: APC Labeled.
Molecular Weight: 27.3 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.3 kDa.
Purity: N/A.
Buffer: PBS, 0.5% BSA, pH7.4.
Storage Conditions: -20℃, aviod light.
Shipping Conditions: RT
