APC Antibody | F47209-0.08ML

APC Antibody | F47209-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This APC antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Immunogen: A portion of amino acids 1148-1176 from the human protein was used as the immunogen for this APC antibody.

Storage: Aliquot the APC antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.