APC Anti-Mouse IL-17A Antibody | DL22972F-1

APC Anti-Mouse IL-17A Antibody | DL22972F-1 | Gentaur US, UK & Europe Disrtribition

Synonyms: Interleukin-17A,Il17a,Ctla8

Reactivity: Mouse

Host: Mouse

Application: ICFCM

Background: The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-22A in vivo.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Mouse IgG1, κ

Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.