Description
APC Anti-Mouse IL-10 Antibody | DL22156F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF
Reactivity: Mouse
Host: Rat
Application: ICFCM
Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.
Concentration: 0.2 mg/mL
Conjugation: APC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Rat IgG2b, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
