Description
APC Anti-Mouse/Human KLRG-1 Antibody | DL22977F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: MAFA, 2F6-Ag
Reactivity: Human, Mouse
Host: Hamster
Application: FCM
Background: Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag) . KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG6 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
Concentration: N/A
Conjugation: APC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Syrian Hamster IgG
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
