Description
APC Anti-Mouse FcεRIα Antibody | DL22054F-4 | Gentaur US, UK & Europe Disrtribition
Synonyms: High affinity immunoglobulin epsilon receptor subunit alpha,Fc-epsilon RI-alpha,FcERI,Fcer1a
Reactivity: Mouse
Host: Armenian Hamster
Application: FCM
Background: FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
Concentration: N/A
Conjugation: APC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Armenian Hamster IgG
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
