APC Anti-Mouse CD366/Tim-3 Antibody | DL22117F-3

APC Anti-Mouse CD366/Tim-3 Antibody | DL22117F-3 | Gentaur US, UK & Europe Disrtribition

Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3

Reactivity: Mouse

Host: Rat

Application: FCM

Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells) . Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Concentration: 0.2 mg/mL

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Rat IgG2a, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.