APC Anti-Human CD206 Antibody | DL21860F-4

APC Anti-Human CD206 Antibody | DL21860F-4 | Gentaur US, UK & Europe Disrtribition

Synonyms: CLEC13D,CLEC13DL,MRC1L1,MMR,hMR

Reactivity: Human

Host: Mouse

Application: FCM

Background: Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR) . It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Mouse IgG1, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.