Description
APC Anti-Human CD11b Antibody | DL21779F-4 | Gentaur US, UK & Europe Disrtribition
Synonyms: Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b
Reactivity: Human
Host: Mouse
Application: FCM
Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Concentration: N/A
Conjugation: APC
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
