APC Anti-Human CD117 Antibody | DL21811F-2

APC Anti-Human CD117 Antibody | DL21811F-2 | Gentaur US, UK & Europe Disrtribition

Synonyms: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117

Reactivity: Human

Host: Mouse

Application: FCM

Background: CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML) . CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Mouse IgG1, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.