Description
AP2 alpha Antibody (TFAP2A, Activator protein 2) | F47549-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This AP2 antibody is available for research use only.
Purity: Antigen affinity
Description: Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Immunogen: A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody.
Storage: Aliquot the AP2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
