Description
Anti-Setd1b polyclonal antibody | 25314 | Gentaur US, UK & Europe Disrtribition
Category: Epigenetics/Antibody
Application: ELISA (1:100 - 1:500)
WB (1:500)
Background: SETD1B (UniProt/Swiss-Prot entry Q9UPS6) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non-overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.
Description: Polyclonal antibody raised in rabbit against mouse Setd1b (Set domain containing 1B), using a 3 KLH-conjugated synthetic peptides containing sequences from the central part of the protein
Product Type: Antibody
Shippement Condition: -20°C or -80°C
