Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) | SAD-S35-100ug

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) | SAD-S35-100ug| Gentaur Distribution US, UK & Europe

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: AntiN/ASARSN/ACoVN/A2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) (SADN/AS35) is isolated from a SARSN/ACoVN/A2 infected patient and is recombinantly produced from human 293 cells (HEK293) . This antibody recognizes the SARSN/ACoVN/A2 Spike Protein RBD domain and inhibits the interaction between SARSN/ACoVN/A2 RBD and ACE2 with an IC50 of 1.47 μg/mL using SARSN/ACoVN/A2 Inhibitor Screening Kit.Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARSN/ACoVN/A2 Spike protein..

Molecule: Spike RBD.

Species: Human.

Tag: Human IgG1 | Kappa.

Conjugate: Unconjugated.

Purity: 95%.

Charactirization: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT