Description
Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AS110) (Delta Specific) (MALS verified) | SPD-M110-1mg| Gentaur Distribution US, UK & Europe
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and BN/Alymphocytes obtained from a mouse immunized with Spike RBD F (ab') 2. The antibody is specific against the Delta (B.1.617.2/AY.4) variant of SARSN/ACoVN/A2, and has no binding with the spike RBD of the wild type virus and the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Omicron (B.1.1.529/BA.1) variant..
Molecule: Spike RBD.
Species: Mouse.
Tag: Mouse IgG1 | Mouse Kappa.
Conjugate: Unconjugated.
Purity: 95%.
Charactirization: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
