Description
Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AS113) (Omicron Specific) | SPD-M415-100ug| Gentaur Distribution US, UK & Europe
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: AntiN/ASARSN/ACoVN/A2 Spike RBD Antibody, Human IgG1 (AS113) (Omicron Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and BN/Alymphocytes obtained from a mouse immunized with omicron Spike RBD. The antibody is specific against the Omicron (B.1.1.529/BA.1) variant of SARSN/ACoVN/A2, and has no binding with the spike RBD of the wild type virus and other viral lineages.
Molecule: Spike RBD.
Species: Human.
Tag: Human IgG1 | Human Kappa.
Conjugate: Unconjugated.
Purity: 95%.
Charactirization: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
