Description
Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 (MALS verified) | SPD-S164-100ug| Gentaur Distribution US, UK & Europe
S protein has two functional regions, S1 and S2. S1 is composed of four domains, including N-amino-terminal domain (NTD) and receptor-binding domain (RBD), and binds to host cell receptor ACE2. Compared with RBD antibody, the neutralization ability of NTD antibody is weak, most of which can recognize the three-dimensional conformation of viral protein. In the NTD region of mutant strains, there are a large number of amino acid deletion and insertion, as well as numerous point mutations, most of which can escape the recognition and neutralization of NTD antibody.
Source: S protein has two functional regions, S1 and S2. S1 is composed of four domains, including NN/AaminoN/Aterminal domain (NTD) and receptorN/Abinding domain (RBD), and binds to host cell receptor ACE2. Compared with RBD antibody, the neutralization ability of NTD antibody is weak, most of which can recognize the threeN/Adimensional conformation of viral protein. In the NTD region of mutant strains, there are a large number of amino acid deletion and insertion, as well as numerous point mutations, most of which can escape the recognition and neutralization of NTD antibody.
Molecule: Spike NTD.
Species: Human.
Tag: Human IgG1 | Human Kappa.
Conjugate: Unconjugated.
Purity: 95%.
Charactirization: PBS, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
