Description
Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (AS41) | NUN-S41-1mg| Gentaur Distribution US, UK & Europe
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68) . The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Source: AntiN/ASARSN/ACoVN/A2 Nucleocapsid Antibody, Human IgG1 (AS41) (NUNN/AS41) is isolated from a SARSN/ACoVN/A2 infected patient and is recombinantly produced from human 293 cells (HEK293) . As verified by binding test with NN/ANTD (Cat. No. NUNN/AC5143) and NN/ACTD (Cat. No. NUNN/AC5145) protein, this antibody can only bind to NN/ACTD (AA Ser 255 N/A Pro 364) . ELISA test validated that this antibody can bind multiple N protein variants (Cat. No. NUNN/AC52H8, NUNN/AC52Hc, NUNN/AC52Hd, NUNN/AC52Hm) with similar affinity as compared to the wild type N protein (Cat. No. NUNN/AC5227) .
Molecule: Nucleocapsid protein.
Species: Human.
Tag: Human IgG1 | Kappa.
Conjugate: Unconjugated.
Purity: 95%.
Charactirization: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
