Anti-PADI4 polyclonal antibody | 25305

Anti-PADI4 polyclonal antibody | 25305 | Gentaur US, UK & Europe Disrtribition

Category: Epigenetics/Antibody

Application: ELISA (1:1000 - 1:5000)
WB (1:1000)

Background: Protein arginine deiminases catalyse the conversion of arginine residues in proteins to citrulline. PADI4 (UniProt/Swiss-Prot entry Q9UM07) catalyses the citrullination-deimination of Arg-8 and Arg-17 from histone H3 and Arg-3 from histone H4. This prevents their methylation by CARM1 and HRMT1L2/PRMT1, thereby repressing transcription. PADI4 also citrullinates EP300/P300 at Arg-2142, which favours its interaction with NCOA2/GRIP.

Description: Polyclonal antibody raised in rabbit against human PADI4 (Protein-arginine deiminase type-4), using a KLH-conjugated synthetic peptide containing a sequence from the N-terminus of the protein

Product Type: Antibody

Shippement Condition: -20°C or -80°C