Description
Anti-MERS-CoV Nucleocapsid Protein Polyclonal Antibody | E-AB-V1282 | Gentaur US, UK & Europe Disrtribition
Category: N/A
Synonyms: coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein
Application: WB
Reactivity: MERS-CoV
Host: Rabbit
Isotype: IgG
Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Lead Time: N/A
Concentration: 1mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Buffer: 0.2 μm filtered solution in PBS
Dillution: WB 1:1000-1:5000
Conjugation: Unconjugated
Immunogen: A synthetic peptide corresponding to the center region of MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein (NP protein)
