Description
Anti-Jarid1b polyclonal antibody | 25293 | Gentaur US, UK & Europe Disrtribition
Category: Epigenetics/Antibody
Application: ELISA (1:100 - 1:200)
WB (1:500)
Background: JARID1B (UniProt/Swiss-Prot entry Q9UGL1) is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor.
Description: Polyclonal antibody raised in rabbit against mouse Jarid1b (Jumonji, AT rich interactive domain 1B), using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein.
Product Type: Antibody
Shippement Condition: -20°C or -80°C
