Description
Anti-Human CD3-FITC/CD4-PE/CD45-PerCP-Cyanine5.5 | DL22674F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: N/A
Reactivity: Human
Host: N/A
Application: FCM
Background: This product is a FCM antibody cocktail made up of FITC Anti-Human CD3 Antibody [Clone: OKT3] (Mouse IgG2a, κ),PE Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ) and PerCP/Cyanine5.5 Anti-Human CD45 Antibody [Clone: HI30] (Mouse IgG1, κ) . CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells. CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection. CD45 is a single-chain type I transmembrane glycoprotein. Except for erythrocytes and platelets, CD45 is expressed on nearly all of the hematopoietic cells with high level. It is a common marker for blood leukocytes. CD45 is a receptor type protein tyrosine phophatase and plays essential roles in B cell and T cells signaling.
Concentration: N/A
Conjugation: FITC,PE,PerCP/Cyanine5.5
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
