Anti-HP1α polyclonal antibody | 25291

Anti-HP1α polyclonal antibody | 25291 | Gentaur US, UK & Europe Disrtribition

Category: Epigenetics/Antibody

Application: WB (1:1000)
IF: (1:500)

Background: HP1 alpha (UniProt/Swiss-Prot entry P45973) is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at Lys-9, leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.

Description: Polyclonal antibody raised in rabbit against human HP1 ? (Heterochromatin protein 1 homolog alpha), using the full length recombinant GST tagged protein

Product Type: Antibody

Shippement Condition: -20°C or -80°C