Description
Anti-HP1α, β and γ polyclonal antibody | 25292 | Gentaur US, UK & Europe Disrtribition
Category: Epigenetics/Antibody
Application: ChIP (4 µg/ChIP)
Background: HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at Lys-9, leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the inner nuclear membrane
Description: Polyclonal antibody raised in rabbit against human HP1β (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the HP1α and HP1γ isoforms.
Product Type: Antibody
Shippement Condition: -20°C or -80°C
