Anti-H3K18ac polyclonal antibody | 25236

Anti-H3K18ac polyclonal antibody | 25236 | Gentaur US, UK & Europe Disrtribition

Category: Epigenetics/Antibody

Application: ELISA (1:100)
DB (1:1000)
WB (1:250)

Background: Acetylation of histone H3 is associated with active gene transcription. Acetylation at H3K18 and H3K24 favors methylation at H3R17me by CARM1/PRMT4. SIRT7 is a chromatin-associated H3K18Ac-specific deacetylase. Studies show a significant correlation between low expression of H3K18ac and better prognosis of patients with oesophageal squamous cell carcinoma.

Description: Polyclonal antibody raised in rabbit against histone H3 containing the acetylated lysine 18 (H3K18ac), using a KLH-conjugated synthetic peptide

Product Type: Antibody

Shippement Condition: -20°C or -80°C