Anti-DNMT1 polyclonal antibody | 25216

Anti-DNMT1 polyclonal antibody | 25216 | Gentaur US, UK & Europe Disrtribition

Category: Epigenetics/Antibody

Application: ELISA (1:100 - 1:1000)
WB (1:500)

Background: DNMT1 (UniProt/Swiss-Prot entry P26358) preferentially methylates CpG residues in hemimethylated DNA and is responsible for maintaining methylation patterns established in development. Inactivation of DNMT1 causes global demethylation and embryonic lethality. DNA methylation is coordinated with methylation of histones. Transcriptional repression by DNMT1 is mediated by direct interaction with HDAC2

Description: Polyclonal antibody raised in rabbit against mouse DNMT1 (DNA (cytosine-5)-methyltransferase 1), using a KLH-conjugated synthetic peptide containing an amino acid sequence from the C-terminal part of the protein

Product Type: Antibody

Shippement Condition: -20°C or -80°C