Description
Anti-CD28 Agonist Antibody (Humanized) | 100186-2 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Antibody
Application: This antibody is useful for activation of CD28 costimulatory pathway in T cells
Background: The T cell-specific receptor CD28 is an important regulator of the immune system. The ligation of CD28 and its ligands CD80/CD86 on the APC provides a critical costimulatory signal alongside T cell receptor (TCR) for T cell activation. The costimulatory signal can also be delivered by the interaction between CD28 and its agonist antibody.
Description: Recombinant monoclonal antibody recognizing human CD28. This antibody binds to CD28 on T cells and promotes T cell response. Not tested in other species. This antibody has been humanized to reduce immunogenicity and improve the therapeutic half-life.
Product Type: Antibody
Shippement Condition: -80°C