Description
Anti-CD22 CAR Lentivirus (Clone m971 ScFv-CD8-4-1BB-CD3ζ) | 78608 | Gentaur US, UK & Europe Disrtribition
Category: CAR-T/Lentivirus
Application: Ideal as a positive control for anti-CD22 CAR evaluation in T cells; useful for transduction optimization.
Background: N/A
Description: The anti-CD22 CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain variable fragment) of anti-CD22 (clone m971) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (below).
Product Type: Lentivirus
Shippement Condition: -80°C
