Description
Anti-CD19/CD22 Bispecific CAR Lentivirus (Clones FMC63/m971 ScFv-CD8-4-1BB-CD3ζ) | 78609 | Gentaur US, UK & Europe Disrtribition
Category: CAR-T/Lentivirus
Application: Ideal as a positive control for anti-CD19/CD22 Bispecific CAR evaluation in T cells Use in transduction optimization Use to generate anti-CD19/CD22 Bispecific CAR-T cells for research use only, not for therapeutic purposes
Background: N/A
Description: The anti-CD19/CD22 Bispecific CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain variable fragments) of anti-CD19 (clone FMC63) and anti-CD22 (clone m971) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains.
Product Type: Lentivirus
Shippement Condition: -80°C
