Anti-CBX2 polyclonal antibody | 25212

Anti-CBX2 polyclonal antibody | 25212 | Gentaur US, UK & Europe Disrtribition

Category: Epigenetics/Antibody

Application: ELISA (1:300)

Background: CBX2 (UniProtKB/Swiss-Prot entry Q14781) is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression.

Description: Polyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein

Product Type: Antibody

Shippement Condition: -20°C or -80°C