Description
Anti-ASH2 polyclonal antibody | 25209 | Gentaur US, UK & Europe Disrtribition
Category: Epigenetics/Antibody
Application: WB (1:1000)
Background: ASH2 (UniProtKB/Swiss-Prot entry Q9UBL3) is a component of the SET1/ASH2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the SET1/ASH2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. ASH2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.
Description: Polyclonal antibody raised in rabbit against human Ash2 (absent, small, or homeotic 2), using a recombinant protein
Product Type: Antibody
Shippement Condition: -20°C or -80°C
