Description
Annexin A1 Monoclonal Antibody | PA6608 | Gentaur US, UK & Europe Disrtribition
Clone : YN00086m
Reactivity : Human
Application : IHC-P
Host : Mouse
Category : RTU for IHC
Concentration : 100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Buffer : TBS with 0.1% Proclin300, PH7.4
Backgound : Annexin A1 is a member of calcium dependent phospholipid binding protein superfamily, which is widely expresseded in human tissues. It is an endogenous anti-inflammatory medium, which plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandin and leukotriene mediators. Annexin A1 can be used to distinguish leukemia from other B-cell lymphoma. The overexpression of Annexin A1 is also frequently found in adenocarcinoma of the esophageal and gastroesophageal junction, which is related to pathological T stage and distal metastasis, and is an independent prognostic indicator.