Description
ANGPTL4 Antibody | F51590-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, FACS, ELISA
Buffer: N/A
Limitation: This ANGPTL4 antibody is available for research use only.
Purity: Purified
Description: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.
Immunogen: A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody.
Storage: Aliquot the ANGPTL4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
