Description
ANGPTL3 Antibody | F49810-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This ANGPTL3 antibody is available for research use only.
Purity: Purified
Description: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Immunogen: A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.
Storage: Aliquot the ANGPTL3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.